Tumor Ppt New: Wilms

: Residual tumor in abdomen (positive nodes, spill, or rupture). Stage IV : Distant hematogenous metastases (Lungs/Liver). Stage V : Bilateral renal involvement. Slide 10: Multidisciplinary Treatment Surgery : Radical nephrectomy + lymph node sampling. Chemotherapy : Vincristine, Dactinomycin +/- Doxorubicin.

Staging for Wilms tumor is based on the anatomical extent of the disease, not genetics, and is crucial for determining postoperative treatment. The table below compares the two systems:

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Found in 25–60% of patients due to increased renin production. Hematuria: Gross or microscopic blood in the urine. General Symptoms: Fever, anorexia, or weight loss. 3. Diagnostic Workup Imaging: wilms tumor ppt new

Wilms Tumor (Nephroblastoma): New Paradigms in Risk-Adapted Management Subtitle: Updated Clinical Guidelines, Molecular Classifications & Emerging Therapeutics (2025–2026) Presented by: [Presenter Name/Institution] Date: [Presentation Date]

: Serum creatinine and BUN to assess baseline kidney function.

Tumor limited to the kidney; excised intact without rupture; renal capsule intact. : Residual tumor in abdomen (positive nodes, spill,

Wilms Tumor, or nephroblastoma, is the most common primary renal malignancy in the pediatric population. This has been designed to provide medical students, pediatric residents, oncology fellows, and practicing clinicians with a comprehensive, evidence-based overview of the disease—from embryology to long-term survivorship. The deck integrates the latest Children’s Oncology Group (COG) and International Society of Paediatric Oncology (SIOP) protocols, reflecting a modern, risk-stratified approach to treatment.

Frequently used in SIOP (International Society of Pediatric Oncology) protocols to shrink tumors before resection, reducing surgical complications.

Radical nephrectomy is the initial treatment, aiming for complete removal without rupturing the tumor. The table below compares the two systems: This

PPT tip: Show a side-by-side comparison of CT (radiation dose) vs. rapid MRI (no sedation in young children).

Wilms tumor often presents incidentally. Recognizing the clinical triad and associated symptoms is vital for prompt diagnostic workups.